Click Here to return To Results

 

Peripheral Neuropathy in Patients with B-Thalassaemia JNNP 54:997-1000, Papanastasiou,D.A.,et al, 1991 See this aricle in Pubmed Article Abstract As some patients with B-thalassaemia manifested neurological signs, clinical and electrophysiological investigations were carried out on 53 thalassaemic patients and 29 healthy control subjects.Twenty per cent of the patients showed clinical and electrophysiological findings of a mild peripheral sensorimotor neuropathy,mainly of the lower limbs.The clinical symptoms were numbness,pins and needles sensations,muscular cramps,myalgia and muscle weakness.The electrophysiological abnormalities were manifested by decreased motor conduction velocity(MCV)and prolonged F-wave latencies of the tibial and the peroneal nerves.Borderline increase in the latencies of the sensory potentials of the median nerve was also observed.The electromyographic findings of the patients with diminished MCVs were compatible with a predominantly motor peripheral neuropathy.This neuropathy appears during the second and third decade of life.

Related Tags

(click to filter results - removes previous filter) hemoglobin abnormality,neurologic complications of nerve conduction studies neuropathy neuropathy,peripheral thalassemia

Click Here to return To Results